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BiologicTx Patient Services  |  Transplant Medications Guide

Transplant Medication Facts

 

After organ transplant, you will take three primary types of medication:

  • Anti-rejection or Immunosuppressants: Medication to keep your body from fighting your new organ. This lowers the body’s immune response, making it less susceptible of destroying the transplanted organ. Rejection of your new transplanted organ is the most serious problem that can occur after transplant. It is important to take the anti-rejection medications consistently and not to miss any doses.
  • Prevent and Treat Infection: Medication to prevent and treat infections that may be caused by anti-rejection medications.
  • Side Effect Treatment: Medication to help treat side effects caused by transplant medications.

 

Medication Re-Order Process

 

Call BiologicTx Pharmacy within 5-7 days of running out of your medication. We will also assist you in the refill process by calling you to set up a refill delivery. However, if you notice you are running low on medication, your doctor has given you a new prescription, or a dose has changed and the pharmacy is unaware, call BiologicTx Pharmacy right away. Your pharmacy team can be reached in person Monday-Friday, 9am-5pm (EST) at: 877-567-8087 and can be available after hours for emergency situations.

 

Medication Reference Guide

 

Anti-Rejection Medications (Immunosuppressives): Decreases immune system’s response to transplanted organ, preventing rejection.

  • CellCept (Mycophenolate Mofetil, MMF) – Take on empty stomach. Do not take at the same time as antacids that contain magnesium or aluminum.
  • Myfortic (Mycophenolic acid delayed release) – Take on empty stomach. Do not take at the same time as antacids that contain magnesium or aluminum.
  • Envarsus XR (Tacrolimus extended release) – Take with a full glass of water on an empty stomach preferably in the morning.  Do not chew, divide, or crush tablets.  Swallow the tablets whole.  Do not take with grapefruit, grapefruit juice, pomegranate, pomegranate juice, or any juice blend that contains grapefruit or pomegranate.
  • Prograf (Tacrolimus) – Take with full glass of water. Do not take with grapefruit or grapefruit juice. Doing so may increase tacrolimus levels. Side effects: headache, hand and feet tingling, high blood sugar, tremors, kidney problems, abnormal electrolytes, itchy rash, sleep problems, and high blood pressure.
  • Rapamune (Sirolimus) – Take with full glass of water. Do not take with grapefruit or grapefruit juice. If also taking Cyclosporine, take this medicine 4 hours after cyclosporine dose.
  • Zortress (Everolimus) – Take with or without food, consistently.
  • Imuran (Azathioprine) – Take with full glass of water. Azathioprine may interact with some other drugs, especially Allopurinol.

 

Cyclosporine: Decreases immune system’s response to a transplanted organ to prevent rejection. Take with full glass of water. Do not take with grapefruit or grapefruit juice. Gengraf and Neoral are not interchangeable with Sandimmune.

 

Steroids: Given along with immunosuppressants for organ transplants to prevent rejection. Take with food or milk.

  • Prednisone
  • Prelone (Prednisolone)
  • Medrol (Methylprednisolone)

 

Prophylaxis/Anti-infective Medications:

  • Bactrim/Septra (Sulfamethoxazole/Trimethoprim, SMZ/TMP) – Prevention and treatment of certain bacterial infections. Take on an empty stomach. Drink plenty of fluids.
  • Mepron (Atovaquone) – For prevention or treatment of certain infections. Take with a full meal or liquid nutritional supplement.
  • Dapsone – For prevention or treatment of certain infections. Take with or without food.

 

Anti-fungal Medications: Prevention and treatment of fungal infections.

  • Diflucan (Fluconazole) – Take with or without food. May interfere with tacrolimus levels. Check with physician or pharmacist.
  • Vfend (Voriconazole) – Take on empty stomach. Check drug interactions with physician and pharmacist, including over-the-counter medications or herbal supplements.
  • Mycelex Troche (Clotrimazole) – Prevention and treatment of fungal infections of the mouth and throat. Place troche in mouth and allow to dissolve slowly (may take 15-30 min).
  • Noxafil (Posaconazole) – Take with full meal or liquid nutritional supplement. Check drug interactions with physician or pharmacist.
  • Nystatin Oral Suspension – Prevention or treatment of fungal infections of the mouth and throat. Swish and swallow after meals as directed. Take full course of treatment.
  • Sporanox (Itraconazole) – Take capsules with food. Take liquid on empty stomach. Check drug interactions with physician or pharmacist.

 

Injectable Medications: Store medication in refrigerator (do not freeze). Clean hands, injection site, and top of vial prior to injection. Do not shake vials.

  • Aranesp (Darbepoetin Alfa) – Treatment of anemia (low hemoglobin levels).
  • Procrit/ Epogen (Epoetin Alfa) – Treatment of anemia (low hemoglobin levels).
  • Neupogen (Filgrastim) – Stimulates production of white blood cells by your bone marrow. Talk to physician if you experience any symptoms of an infection which may include: chills, sore throat, congestion or fever.

 

Anti-Viral Medications: Prevention and treatment of certain viral infections.

  • Cytovene (Ganciclovir) – Take with food and full glass of water. If sore throat, fever, unusual bleeding or bruising occurs, contact physician immediately.
  • Zovirax (Acyclovir) – Take with or without food.
  • Valcyte (Valganciclovir) – Take with food and full glass of water. Do not break or crush tablets.
  • Valtrex (Valacyclovir) – Take with or without food.

 

Anti-Hypertensive Medications: Treatment of high blood pressure. After taking, rise from seated or lying position slowly.

  • Cardizem (Diltiazem)
  • Cardua (Doxazosin)
  • Catapres (Clonidine)
  • DynaCirc (Isradipine)
  • Hytrin (Terazosin)
  • Lopressor (Metoprolol)
  • Norvasc (Amlodipine)
  • Prinivil (Lisinopril)
  • Procardia (Nifedipine)
  • Cozaar (Losartan)
  • Diovan (Valsartan)
  • Tenormin (Atenolol)
  • Vasotec (Enalapril)
  • Altace (Ramipril)
  • Cardene (Nicardipine)
  • Calan (Verapamil)
  • Lotensin (Benazepril)
  • Avapro (Irbesartan)

 

Cholesterol Reducing Medications: Lower levels of fats and cholesterol in the blood. Take with food. Avoid grapefruit products with “statin” medications.

  • Lipitor (Atorvastatin)
  • Mevacor (Lovastatin)
  • Lovaza (Omega-3 Fatty Acid)
  • Pravachol (Pravastatin)
  • Antara, Fenoglide, Lofibra, Lipofen, Tricor (Fenofibrate)
  • Zocor (Simvastatin)
  • Crestor (Rosuvastatin)
  • Vytorin (Simvastatin/Ezetimbe)
  • Zetia (Ezetimbe)
  • Welchol (Colesevelam)

 

Anti-Ulcer Medication: Treatment or prevention of stomach ulcers and related conditions. Best taken on empty stomach.

  • Aciphex (Rabeprazole)
  • Nexium (Esomeprazole)
  • Pepcid (Famotidine)
  • Prevacid (Lansoprazole)
  • Prilosec (Omeprazole)
  • Protonix (Pantoprazole)
  • Tagamet (Cimetidine)
  • Zantac (Ranitidine)
  • Zegerid (Omeprazole; Sodium Bicarbonate)
  • Kapidex (Dexlansprazole)

 

Stool Softeners: Prevention and treatment of constipation. Avoid if bowel obstruction is suspected. Maintain adequate fluid and fiber intake.

  • Colace (Docusate)